Rav Ḥisda strongly objects to this opinion: Do you think that after one fills his belly with lettuce, he then recites another blessing over it? Rather, Rav Ḥisda said: Initially one recites two blessings over the lettuce: Who creates fruit of the ground, and: Commanded us over eating bitter herbs, and he eats it; and later in the seder he eats lettuce without a blessing.

The Gemara comments: In Syria, they act in accordance with the opinion of Rav Huna. And Rav Sheshet, son of Rav Yehoshua, acted in accordance with the opinion of Rav Ḥisda. The Gemara summarizes: And the halakha is in accordance with the opinion of Rav Ḥisda. The Gemara relates that Rav Aḥa, son of Rava, would seek other vegetables for Passover to preclude himself from taking sides in the dispute. He first recited only the blessing: Who creates fruit of the ground, and later added the blessing: Commanded us over eating bitter herbs, thereby satisfying all opinions.

Ravina said: Rav Mesharshiya, son of Rav Natan, said to me that Hillel said as follows, citing tradition: A person should not wrap matza and bitter herbs together and eat them. He ruled in this manner because he maintains that today, after the destruction of the Temple, the obligation to eat matza applies by Torah law, and the obligation to eat bitter herbs without the Paschal lamb applies by rabbinic law. And if one were to wrap them together, the bitter herbs, whose obligation applies by rabbinic law, would come and nullify the matza, whose obligation applies by Torah law.

And even according to the one who says that mitzvot do not nullify each other, that principle applies only to a mixture of one food whose obligation applies by Torah law with another food whose obligation applies by Torah law, or to a mixture of one food whose obligation applies by rabbinic law with another food whose obligation applies by rabbinic law. However, in a case of a mixture of one food whose obligation applies by Torah law with another food whose obligation applies by rabbinic law, the food whose obligation applies by rabbinic law comes and nullifies the food whose obligation applies by Torah law.

The Gemara asks: Who is the tanna that you heard say that mitzvot do not nullify each other? It is Hillel, as it was taught in a baraita: They said about Hillel that he would wrap matza and bitter herbs together and eat them, as it is stated: “They shall eat it with matzot and bitter herbs” (Numbers 9:11), which indicates that these two foods should be consumed together.

Rabbi Yoḥanan said: Hillel’s colleagues disagree with him, as it was taught in another baraita: I might have thought that one should wrap matzot and bitter herbs together and eat them in the manner that Hillel eats them; therefore the verse states: “They shall eat it with matzot and bitter herbs,” meaning that one may eat even this, the matza, by itself, and that, the bitter herbs, by themselves. Rav Ashi strongly objects to this proof: If so, if the Sages disagree with Hillel and maintain that mitzvot nullify each other, what is the meaning of the word even in this baraita? This wording indicates that Hillel’s opinion is not rejected entirely, but that one fulfills his obligation even if he eats the items without combining them.

Rather, Rav Ashi said: This is what this tanna is teaching: I might have thought that one fulfills his obligation with them only if he wraps matzot and bitter herbs together and eats them in the manner that Hillel eats them. Therefore, the verse states: “They shall eat it with matzot and bitter herbs,” i.e., one fulfills his obligation even if he eats the matza by itself and the bitter herbs by themselves.

The Gemara comments: Now that the halakha was stated neither in accordance with the opinion of Hillel nor in accordance with the opinion of the Rabbis, one recites the blessing: Commanded us over eating matza, and eats matza to fulfill his obligation. And then he recites the blessing: Commanded us over eating bitter herbs, and eats the lettuce as bitter herbs. And then he eats matza and lettuce together without a blessing in remembrance of the Temple, in the manner of Hillel in the days of the Temple, who ate matza and bitter herbs together with the Paschal lamb.

Rabbi Elazar said that Rav Oshaya said: Anything that is dipped in a liquid before it is eaten requires the ritual of washing of the hands. The obligation to wash one’s hands was instituted to preserve ritual purity and to prevent people from causing teruma food to contract ritual impurity. Hands are generally considered impure to the second degree of ritual impurity, and they confer impurity upon any liquid with which they come in contact. Liquids that become ritually impure are automatically impure to the first degree and will therefore transfer ritual impurity to any food that is dipped in them. Rav Pappa said: Learn from this halakha, which requires the washing of hands, that for this lettuce on Passover,